Description

WHAT IS NEMBUTAL?

NEMBUTAL Sodium Solution (pentobarbital sodium injection) is a sterile solution for intravenous or intramuscular injection. Each mL contains pentobarbital sodium 50 mg, in a vehicle of propylene glycol, 40%, alcohol, 10% and water for injection, to volume. Factors of consideration are the patient’s age, weight, and condition. Use parenteral routes only when oral administration is impossible or impractical.

Intramuscular Administration

Make IM injection of the sodium salts of barbiturates get deeply into a large muscle, and a volume of 5 mL is the limit at any one site because of possible tissue irritation. After IM injection of a hypnotic dose, monitor the patient’s vital signs so as to avoid any unusual situation. The usual adult dosage of NEMBUTAL (pentobarbital) Sodium Solution is 150 to 200 mg as a single IM injection; the pediatric dosage ranges from 2 to 6 mg/kg as a single IM injection not to exceed 100 mg.

Intravenous Administration

NEMBUTAL IV injection don’t get along with conditions in which other routes are not feasible, either because the patient is unconscious (as in cerebral hemorrhage, eclampsia, or status epilepticus), or because the patient resists (as in delirium), or because prompt action is imperative. Slow IV injection is essential, and patients have to be carefully observed during administration. This requires that blood pressure, respiration, and cardiac function be maintained, vital signs be recorded, and equipment for resuscitation and artificial ventilation be available.

The rate of IV injection must not exceed 50 mg/min for pentobarbital sodium. The possibility of overdose and respiratory depression is remote when you ingest the drug slowly in fractional doses. It has a common use by initial dose for the 70 kg adult is 100 mg. . At least one minute is necessary to determine the full effect of intravenous pentobarbital. This is one of the most intriguing meds you will ever come across